Unifying candidate gene and GWAS Approaches in Asthma.

Unifying candidate gene and GWAS Approaches in Asthma.

The first genome wide association study (GWAS) for childhood asthma identified a novel major susceptibility locus on chromosome 17q21 harboring the ORMDL3 gene, but the role of previous asthma candidate genes was not specifically analyzed in this GWAS. We systematically identified 89 SNPs in 14 cand...

Full description

Bibliographic Details
Main Authors: Sven Michel, Liming Liang, Martin Depner, Norman Klopp, Andreas Ruether, Ashish Kumar, Michaela Schedel, Christian Vogelberg, Erika von Mutius, Andrea von Berg, Albrecht Bufe, Ernst Rietschel, Andrea Heinzmann, Otto Laub, Burkhard Simma, Thomas Frischer, Jon Genuneit, Ivo G Gut, Stefan Schreiber, Mark Lathrop, Thomas Illig, Michael Kabesch
Format: Article
Language:English
Published: Public Library of Science (PLoS) 2010-01-01
Series:PLoS ONE
Online Access:http://europepmc.org/articles/PMC2980484?pdf=render

Internet

http://europepmc.org/articles/PMC2980484?pdf=render

Similar Items