Multiple Property Tolerance Analysis for the Evaluation of Missense Mutations
Computational prediction of the impact of a mutation on protein function is still not accurate enough for clinical diagnostics without additional human expert analysis. Sequence alignment-based methods have been extensively used but their results highly depend on the quality of the input alignments...
Main Authors: | , , , |
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Format: | Article |
Language: | English |
Published: |
SAGE Publishing
2006-01-01
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Series: | Evolutionary Bioinformatics |
Online Access: | http://la-press.com/article.php?article_id=126 |