Plasminogen mediates communication between the peripheral and central immune systems during systemic immune challenge with lipopolysaccharide

Abstract Background Systemic inflammation has been implicated in the progression of many neurodegenerative diseases and may be an important driver of the disease. Dementia and cognitive decline progress more rapidly following acute systemic infection, and systemic inflammation midlife is predictive...

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Bibliographic Details
Main Authors: Sarah K. Baker, Zu-Lin Chen, Erin H. Norris, Sidney Strickland
Format: Article
Language:English
Published: BMC 2019-08-01
Series:Journal of Neuroinflammation
Subjects:
Online Access:http://link.springer.com/article/10.1186/s12974-019-1560-y