The calpain inhibitor MDL28170 induces the expression of apoptotic markers in Leishmania amazonensis promastigotes.

The calpain inhibitor MDL28170 induces the expression of apoptotic markers in Leishmania amazonensis promastigotes.

Human cutaneous leishmaniasis is caused by distinct species, including Leishmania amazonensis. Treatment of cutaneous leishmaniasis is far from satisfactory due to increases in drug resistance and relapses, and toxicity of compounds to the host. As a consequence for this situation, the development o...

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Bibliographic Details
Main Authors: Fernanda A Marinho, Keyla C S Gonçalves, Simone S C Oliveira, Diego S Gonçalves, Filipe P Matteoli, Sergio H Seabra, Ana Carolina S Oliveira, Maria Bellio, Selma S Oliveira, Thaïs Souto-Padrón, Claudia M d'Avila-Levy, André L S Santos, Marta H Branquinha
Format: Article
Language:English
Published: Public Library of Science (PLoS) 2014-01-01
Series:PLoS ONE
Online Access:http://europepmc.org/articles/PMC3909198?pdf=render

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http://europepmc.org/articles/PMC3909198?pdf=render

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