Single-Gene Congenic Strain Reveals the Effect of Zbtb16 on Dexamethasone-Induced Insulin Resistance

Single-Gene Congenic Strain Reveals the Effect of Zbtb16 on Dexamethasone-Induced Insulin Resistance

BackgroundGlucocorticoids (GCs) are potent therapeutic agents frequently used for treatment of number of conditions, including hematologic, inflammatory, and allergic diseases. Both their therapeutic and adverse effects display significant interindividual variation, partially attributable to genetic...

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Bibliographic Details
Main Authors: Michaela Krupková, František Liška, Ludmila Kazdová, Lucie Šedová, Adéla Kábelová, Drahomíra Křenová, Vladimír Křen, Ondřej Šeda
Format: Article
Language:English
Published: Frontiers Media S.A. 2018-04-01
Series:Frontiers in Endocrinology
Subjects:
ZBTB16
dexamethasone
rat models
congenic strain
pharmacogenetics and pharmacogenomics
insulin resistance
Online Access:http://journal.frontiersin.org/article/10.3389/fendo.2018.00185/full

Internet

http://journal.frontiersin.org/article/10.3389/fendo.2018.00185/full

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