Commensal microbiota maintains alveolar macrophages with a low level of CCL24 production to generate anti-metastatic tumor activity

Abstract Microbiota maintains host tissue homeostasis and influences tissue-resident macrophages. However, the mechanisms by which commensal bacteria in regulating the alveolar macrophages remain unclear. Here, by using an antibiotic-treated (Abt) mouse model, we found commensal bacteria depletion i...

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Bibliographic Details
Main Authors: Min Cheng, Yongyan Chen, Liang Wang, Wen Chen, Ling Yang, Guodong Shen, Tingjuan Xu, Gan Shen, Zhigang Tian, Shilian Hu
Format: Article
Language:English
Published: Nature Publishing Group 2017-08-01
Series:Scientific Reports
Online Access:https://doi.org/10.1038/s41598-017-08264-8