The ECM Modulator ITIH5 Affects Cell Adhesion, Motility and Chemotherapeutic Response of Basal/Squamous-Like (BASQ) Bladder Cancer Cells

The ECM Modulator ITIH5 Affects Cell Adhesion, Motility and Chemotherapeutic Response of Basal/Squamous-Like (BASQ) Bladder Cancer Cells

This study aims at characterizing the role of the putative tumor suppressor ITIH5 in basal-type bladder cancers (BLCA). By sub-classifying TCGA BLCA data, we revealed predominant loss of ITIH5 expression in the basal/squamous-like (BASQ) subtype. ITIH5 expression inversely correlated with basal-type...

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Bibliographic Details
Main Authors: Michael Rose, Erik Noetzel, Jennifer Kistermann, Julian Eschenbruch, Sandra Rushrush, Lin Gan, Ruth Knüchel, Nadine T. Gaisa, Edgar Dahl
Format: Article
Language:English
Published: MDPI AG 2021-04-01
Series:Cells
Subjects:
bladder cancer
BASQ subtype
ITIH5
hyaluronan
CD44
chemosensitizer
Online Access:https://www.mdpi.com/2073-4409/10/5/1038

Internet

https://www.mdpi.com/2073-4409/10/5/1038

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