Synthesis, Characterization, X-ray Crystallography, Acetyl Cholinesterase Inhibition and Antioxidant Activities of Some Novel Ketone Derivatives of Gallic Hydrazide-Derived Schiff Bases

Synthesis, Characterization, X-ray Crystallography, Acetyl Cholinesterase Inhibition and Antioxidant Activities of Some Novel Ketone Derivatives of Gallic Hydrazide-Derived Schiff Bases

Alzheimer’s disease (AD) is the most common form of dementia among older people and the pathogenesis of this disease is associated with oxidative stress. Acetylcholinesterase inhibitors with antioxidant activities are considered potential treatments for AD. Some novel ketone derivatives of gallic hy...

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Bibliographic Details
Main Authors: Hamid Khaledi, Siddig Ibrahim Abdelwahab, Pouya Hassandarvish, A. Hamid A. Hadi, Abeer A. Alhadi, Wageeh A. Yehye, Rozana Othman, Lip Yong Chung, Sri Devi Sukumaran, Mahmood Ameen Abdulla, Nura Suleiman Gwaram, Michael J. C. Buckle, Hapipah Mohd Ali
Format: Article
Language:English
Published: MDPI AG 2012-02-01
Series:Molecules
Subjects:
gallic hydrazide Schiff bases
AChE inhibition
antioxidant study
molecular docking
Online Access:http://www.mdpi.com/1420-3049/17/3/2408/

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http://www.mdpi.com/1420-3049/17/3/2408/

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