Regulation of DNA replication within the immunoglobulin heavy-chain locus during B cell commitment.
The temporal order of replication of mammalian chromosomes appears to be linked to their functional organization, but the process that establishes and modifies this order during cell differentiation remains largely unknown. Here, we studied how the replication of the Igh locus initiates, progresses,...
| Main Authors: | , , , , , , , |
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| Format: | Article |
| Language: | English |
| Published: |
Public Library of Science (PLoS)
2012-07-01
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| Series: | PLoS Biology |
| Online Access: | http://europepmc.org/articles/PMC3393677?pdf=render |