Detection and characterization of estradiol (E2) and unconjugated estriol (uE3) immunoassay interference due to anti-bovine alkaline phosphatase (ALP) antibodies

Detection and characterization of estradiol (E2) and unconjugated estriol (uE3) immunoassay interference due to anti-bovine alkaline phosphatase (ALP) antibodies

Objectives: Competitive immunoenyzmatic assays for estradiol (E2) and unconjugated estriol (uE3) on UniCel DxI 800 Access immunoassay systems (Beckman Coulter) utilize bovine alkaline phosphatase (ALP) for amplification. In these assays, rare ‘IND’ error flags indicate that a relative light unit (RL...

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Bibliographic Details
Main Authors: Anu S. Maharjan, Sara P. Wyness, Julie A. Ray, Tanya L. Willcox, Jonathan D. Seiter, Jonathan R. Genzen
Format: Article
Language:English
Published: Elsevier 2019-11-01
Series:Practical Laboratory Medicine
Online Access:http://www.sciencedirect.com/science/article/pii/S2352551719300502

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http://www.sciencedirect.com/science/article/pii/S2352551719300502

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