Pathways to defense metabolites and evading fruit bitterness in genus Solanum evolved through 2-oxoglutarate-dependent dioxygenases

Pathways to defense metabolites and evading fruit bitterness in genus Solanum evolved through 2-oxoglutarate-dependent dioxygenases

Steroidal glycoalkaloids (SGAs) accumulate in Solanum, but their hydroxylating enzymes are unknown. Here, the authors report 2-OXOGLUTARATE DEPENDENT DIOXYGENASE enzymes that catalyze the committed hydroxylation steps in the biosynthesis of leptinine insecticidal compounds in wild potato or non-bitt...

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Bibliographic Details
Main Authors: Pablo D. Cárdenas, Prashant D. Sonawane, Uwe Heinig, Adam Jozwiak, Sayantan Panda, Bekele Abebie, Yana Kazachkova, Margarita Pliner, Tamar Unger, Dalia Wolf, Itai Ofner, Ester Vilaprinyo, Sagit Meir, Olga Davydov, Amit Gal-on, Saul Burdman, Ashok Giri, Dani Zamir, Tali Scherf, Jedrzej Szymanski, Ilana Rogachev, Asaph Aharoni
Format: Article
Language:English
Published: Nature Publishing Group 2019-11-01
Series:Nature Communications
Online Access:https://doi.org/10.1038/s41467-019-13211-4

Internet

https://doi.org/10.1038/s41467-019-13211-4

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