Small-scale perfusion bioreactor of red blood cells for dynamic studies of cellular pathways: proof-of-concept

Small-scale perfusion bioreactor of red blood cells for dynamic studies of cellular pathways: proof-of-concept

To date, the development of bioreactors for the study of red blood cells (RBCs, daily transfused in the case of disease or hemorrhage) has focused on hematopoietic stem cells. Despite the fact that mature RBCs are enucleated and do not expand, they possess complex cellular and metabolic pathways, as...

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Bibliographic Details
Main Authors: Michel ePrudent, Frédéric eStauber, Alexis eRapin, Sonia eHallen, Nicole ePham, Mélanie eAbonnenc, Laure eMarvin, Bertrand eRochat, Jean-Daniel eTissot, Niels eLion
Format: Article
Language:English
Published: Frontiers Media S.A. 2016-03-01
Series:Frontiers in Molecular Biosciences
Subjects:
Metabolism
bioreactor
erythrocyte
transfusion
storage
Online Access:http://journal.frontiersin.org/Journal/10.3389/fmolb.2016.00011/full

Internet

http://journal.frontiersin.org/Journal/10.3389/fmolb.2016.00011/full

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