Mediation analysis with a time-to-event outcome: a review of use and reporting in healthcare research

Mediation analysis with a time-to-event outcome: a review of use and reporting in healthcare research

Abstract Background Mediation analysis tests whether the relationship between two variables is explained by a third intermediate variable. We sought to describe the usage and reporting of mediation analysis with time-to-event outcomes in published healthcare research. Methods A systematic search of...

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Bibliographic Details
Main Authors: Lauren Lapointe-Shaw, Zachary Bouck, Nicholas A. Howell, Theis Lange, Ani Orchanian-Cheff, Peter C. Austin, Noah M. Ivers, Donald A. Redelmeier, Chaim M. Bell
Format: Article
Language:English
Published: BMC 2018-10-01
Series:BMC Medical Research Methodology
Subjects:
Mediation
Indirect effect
Counterfactuals
Reporting
Mediation analysis, Survival, Time-to-event, Methodology
Online Access:http://link.springer.com/article/10.1186/s12874-018-0578-7

Internet

http://link.springer.com/article/10.1186/s12874-018-0578-7

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