Aryl hydrocarbon receptor (AhR) and its endogenous agonist – indoxyl sulfate in chronic kidney disease

The indoxyl sulfate (IS, indoxyl sulphate) is the end product of dietary tryptophan degradation by indole pathway and significantly higher serum and tissue concentrations of this compound is observed in patients with impaired renal function. Despite the high albumin binding affinity, the remaining f...

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Bibliographic Details
Main Authors: Tomasz Kamiński, Małgorzata Michałowska, Dariusz Pawlak
Format: Article
Language:English
Published: Index Copernicus International S.A. 2017-07-01
Series:Postępy Higieny i Medycyny Doświadczalnej
Subjects:
AhR
Online Access:http://phmd.pl/gicid/01.3001.0010.3843