A bacterial toxin-antitoxin module is the origin of inter-bacterial and inter-kingdom effectors of Bartonella.

Host-targeting type IV secretion systems (T4SS) evolved from conjugative T4SS machineries that mediate interbacterial plasmid transfer. However, the origins of effectors secreted by these virulence devices have remained largely elusive. Previous work showed that some effectors exhibit homology to to...

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Bibliographic Details
Main Authors: Alexander Harms, Marius Liesch, Jonas Körner, Maxime Québatte, Philipp Engel, Christoph Dehio
Format: Article
Language:English
Published: Public Library of Science (PLoS) 2017-10-01
Series:PLoS Genetics
Online Access:http://europepmc.org/articles/PMC5675462?pdf=render