Long-Term Safety and Efficacy of Single or Repeated Intra-Articular Injection of Allogeneic Neonatal Mesenchymal Stromal Cells for Managing Pain and Lameness in Moderate to Severe Canine Osteoarthritis Without Anti-inflammatory Pharmacological Support: Pilot Clinical Study

Long-Term Safety and Efficacy of Single or Repeated Intra-Articular Injection of Allogeneic Neonatal Mesenchymal Stromal Cells for Managing Pain and Lameness in Moderate to Severe Canine Osteoarthritis Without Anti-inflammatory Pharmacological Support: Pilot Clinical Study

Objective: To explore the long-term safety and efficacy of canine allogeneic mesenchymal stromal cells (MSC) administered intra-articularly as single or repeated injections in appendicular joints of dogs affected by moderate to severe refractory osteoarthritis.Study Design: 22 pet dogs were recruite...

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Bibliographic Details
Main Authors: Quentin Cabon, Marine Febre, Niels Gomez, Thibaut Cachon, Paul Pillard, Claude Carozzo, Nathalie Saulnier, Clément Robert, Véronique Livet, Rodolphe Rakic, Nadia Plantier, Philippe Saas, Stéphane Maddens, Eric Viguier
Format: Article
Language:English
Published: Frontiers Media S.A. 2019-02-01
Series:Frontiers in Veterinary Science
Subjects:
mesenchymal stem/stromal cell
allogeneic
osteoarthritis
long-term follow up
neonatal stem cell
lameness
Online Access:https://www.frontiersin.org/article/10.3389/fvets.2019.00010/full

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https://www.frontiersin.org/article/10.3389/fvets.2019.00010/full

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