Sumoylation Inhibits the Growth Suppressive Properties of Ikaros.

Sumoylation Inhibits the Growth Suppressive Properties of Ikaros.

The Ikaros transcription factor is a tumor suppressor that is also important for lymphocyte development. How post-translational modifications influence Ikaros function remains partially understood. We show that Ikaros undergoes sumoylation in developing T cells that correspond to mono-, bi- or poly-...

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Bibliographic Details
Main Authors: Apostol Apostolov, Isma Litim-Mecheri, Attila Oravecz, Marie Goepp, Peggy Kirstetter, Patricia Marchal, Antoine Ittel, Laurent Mauvieux, Susan Chan, Philippe Kastner
Format: Article
Language:English
Published: Public Library of Science (PLoS) 2016-01-01
Series:PLoS ONE
Online Access:http://europepmc.org/articles/PMC4912065?pdf=render

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http://europepmc.org/articles/PMC4912065?pdf=render

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