Generation of Potent Anti-Vascular Endothelial Growth Factor Neutralizing Antibodies from Mouse Phage Display Library for Cancer Therapy
Vascular endothelial growth factor (VEGF) is an important stimulator for angiogenesis in solid tumors. Blocking VEGF activity is an effective therapeutic strategy to inhibit tumor growth and metastasis. Avastin, a humanized monoclonal antibody recognizes VEGF, has been approved by the US Food and Dr...
Main Authors: | Yan-Da Lai, Yen-Yu Wu, Yi-Jiue Tsai, Yi-San Tsai, Yu-Ying Lin, Szu-Liang Lai, Chao-Yang Huang, Ying-Yung Lok, Chih-Yung Hu, Jiann-Shiun Lai |
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Format: | Article |
Language: | English |
Published: |
MDPI AG
2016-02-01
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Series: | International Journal of Molecular Sciences |
Subjects: | |
Online Access: | http://www.mdpi.com/1422-0067/17/2/214 |
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