Greater physiological and behavioral effects of interrupted stress pattern compared to daily restraint stress in rats.

Repeated stress can trigger a range of psychiatric disorders, including anxiety. The propensity to develop abnormal behaviors after repeated stress is related to the severity, frequency and number of stressors. However, the pattern of stress exposure may contribute to the impact of stress. In additi...

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Bibliographic Details
Main Authors: Wei Zhang, Andrea Hetzel, Bijal Shah, Derek Atchley, Shannon R Blume, Mallika A Padival, J Amiel Rosenkranz
Format: Article
Language:English
Published: Public Library of Science (PLoS) 2014-01-01
Series:PLoS ONE
Online Access:http://europepmc.org/articles/PMC4094544?pdf=render