High-level dietary cadmium exposure is associated with global DNA hypermethylation in the gastropod hepatopancreas.

5-methylcytosine (5mC) is a key epigenetic mark which influences gene expression and phenotype. In vertebrates, this epigenetic mark is sensitive to Cd exposure, but there is no information linking such an event with changes in global 5mC levels in terrestrial gastropods despite their importance as...

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Bibliographic Details
Main Authors: Dragos V Nica, Cristina Popescu, George A Draghici, Florina-Maria Andrica, Ionela A Privistirescu, Iosif I Gergen, Reinhard Stöger
Format: Article
Language:English
Published: Public Library of Science (PLoS) 2017-01-01
Series:PLoS ONE
Online Access:http://europepmc.org/articles/PMC5587323?pdf=render