First insight into the kinome of human regulatory T cells.

Regulatory T cells (Tregs) are essential for controlling peripheral tolerance by the active suppression of various immune cells including conventional T effector cells (Teffs). Downstream of the T cell receptor (TCR), more than 500 protein kinases encoded by the human genome have to be considered in...

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Bibliographic Details
Main Authors: Sebastian König, Michael Probst-Kepper, Tobias Reinl, Andreas Jeron, Jochen Huehn, Burkhart Schraven, Lothar Jänsch
Format: Article
Language:English
Published: Public Library of Science (PLoS) 2012-01-01
Series:PLoS ONE
Online Access:http://europepmc.org/articles/PMC3397934?pdf=render