Antibiotic treatment in acute exacerbation of COPD: patient outcomes with amoxicillin vs. amoxicillin/clavulanic acid—data from 43,636 outpatients

Abstract Background For antibiotic treatment of Acute exacerbations of COPD (AECOPD) the National guidelines in Denmark recommend either first choice amoxicillin 750 mg TID (AMX) or amoxicillin with clavulanic acid 500 mg/125 mg TID (AMC). Addition of clavulanic acid offers a broader spectrum; oppos...

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Main Authors: Kristian Bagge, Pradeesh Sivapalan, Josefin Eklöf, Frederik Böetius Hertz, Christian Østergaard Andersen, Ejvind Frausing Hansen, Jens Otto Jarløv, Jens-Ulrik Stæhr Jensen
Format: Article
Language:English
Published: BMC 2021-01-01
Series:Respiratory Research
Online Access:https://doi.org/10.1186/s12931-020-01606-7