α-Actinin1 promotes tumorigenesis and epithelial-mesenchymal transition of gastric cancer via the AKT/GSK3β/β-Catenin pathway

α-Actinin1 promotes tumorigenesis and epithelial-mesenchymal transition of gastric cancer via the AKT/GSK3β/β-Catenin pathway

α-Actinin1 (ACTN1), an actin cross-linking protein, is implicated in cytokinesis, cell adhesion, and cell migration. In addition, it is involved in the tumorigenesis and development of certain cancers, such as breast cancer. We explored the function of ACTN1 in gastric cancer (GC), which has largely...

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Bibliographic Details
Main Authors: Siwen Zhang, Junfu Wang, Ting Chen, Jiancheng Wang, Ye Wang, Zhu Yu, Kun Zhao, Kaitian Zheng, Yeyang Chen, Zhen Wang, Bopei Li, Congjun Wang, Weijia Huang, Zhao Fu, Junqiang Chen
Format: Article
Language:English
Published: Taylor & Francis Group 2021-01-01
Series:Bioengineered
Subjects:
gastric cancer
α-actinin1
epithelial-to-mesenchymal transition
akt/gsk3β/β-catenin
apoptosis
Online Access:http://dx.doi.org/10.1080/21655979.2021.1967713

Internet

http://dx.doi.org/10.1080/21655979.2021.1967713

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