Is human blood a good surrogate for brain tissue in transcriptional studies?

<p>Abstract</p> <p>Background</p> <p>Since human brain tissue is often unavailable for transcriptional profiling studies, blood expression data is frequently used as a substitute. The underlying hypothesis in such studies is that genes expressed in brain tissue leave a...

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Bibliographic Details
Main Authors: van den Berg Leonard H, Luo Rui, Oldham Michael C, Fuller Tova F, Langfelder Peter, Cai Chaochao, Ophoff Roel A, Horvath Steve
Format: Article
Language:English
Published: BMC 2010-10-01
Series:BMC Genomics
Online Access:http://www.biomedcentral.com/1471-2164/11/589