Acquired antibody responses against Plasmodium vivax infection vary with host genotype for duffy antigen receptor for chemokines (DARC).

BACKGROUND:Polymorphism of the Duffy Antigen Receptor for Chemokines (DARC) is associated with susceptibility to and the severity of Plasmodium vivax malaria in humans. P. vivax uses DARC to invade erythrocytes. Individuals lacking DARC are 'resistant' to P. vivax erythrocytic infection. H...

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Bibliographic Details
Main Authors: Amanda Maestre, Carlos Muskus, Victoria Duque, Olga Agudelo, Pu Liu, Akihide Takagi, Francis B Ntumngia, John H Adams, Kim Lee Sim, Stephen L Hoffman, Giampietro Corradin, Ivan D Velez, Ruobing Wang
Format: Article
Language:English
Published: Public Library of Science (PLoS) 2010-07-01
Series:PLoS ONE
Online Access:http://europepmc.org/articles/PMC2896388?pdf=render