Kallikrein-related peptidases 6 and 10 are elevated in cerebrospinal fluid of patients with Alzheimer’s disease and associated with CSF-TAU and FDG-PET

Kallikrein-related peptidases 6 and 10 are elevated in cerebrospinal fluid of patients with Alzheimer’s disease and associated with CSF-TAU and FDG-PET

Abstract Background Alterations in the expression of human kallikrein-related peptidases (KLKs) have been described in patients with Alzheimer’s disease (AD). We elucidated the suitability of KLK6, KLK8 and KLK10 to distinguish AD from NC and explored associations with established AD biomarkers. Met...

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Bibliographic Details
Main Authors: Oliver Goldhardt, Inanna Warnhoff, Igor Yakushev, Ilijana Begcevic, Hans Förstl, Viktor Magdolen, Antoninus Soosaipillai, Eleftherios Diamandis, Panagiotis Alexopoulos, Timo Grimmer
Format: Article
Language:English
Published: BMC 2019-08-01
Series:Translational Neurodegeneration
Subjects:
Alzheimer’s disease (AD)
Kallikrein-like peptidase (KLK)
KLK6
KLK8
KLK10
Cerebral amyloid load
Online Access:http://link.springer.com/article/10.1186/s40035-019-0168-6

Internet

http://link.springer.com/article/10.1186/s40035-019-0168-6

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