High fms-like tyrosine kinase-3 (FLT3) receptor surface expression predicts poor outcome in FLT3 internal tandem duplication (ITD) negative patients in adult acute myeloid leukaemia: A prospective pilot study from India

High fms-like tyrosine kinase-3 (FLT3) receptor surface expression predicts poor outcome in FLT3 internal tandem duplication (ITD) negative patients in adult acute myeloid leukaemia: A prospective pilot study from India

Background & objectives: Mutations in fms-like tyrosine kinase 3 (FLT3) receptor have significant role in assessing outcome in patients with acute myeloid leukaemia (AML). Data for FLT3 surface expression in relation to FLT3 internal tandem duplication (ITD) status and outcome are not available...

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Bibliographic Details
Main Authors: Surender Kumar Sharawat, Vinod Raina, Lalit Kumar, Atul Sharma, Radhika Bakhshi, Sreenivas Vishnubhatla, Ritu Gupta, Sameer Bakhshi
Format: Article
Language:English
Published: Wolters Kluwer Medknow Publications 2016-01-01
Series:Indian Journal of Medical Research
Subjects:
Acute myeloid leukaemia - FLT3 ITD - flowcytometry - PCR - prognosis
Online Access:http://www.ijmr.org.in/article.asp?issn=0971-5916;year=2016;volume=143;issue=7;spage=11;epage=16;aulast=Sharawat

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http://www.ijmr.org.in/article.asp?issn=0971-5916;year=2016;volume=143;issue=7;spage=11;epage=16;aulast=Sharawat

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