Phenotypic and genetic associations between anhedonia and brain structure in UK Biobank

Abstract Anhedonia is a core symptom of multiple psychiatric disorders and has been associated with alterations in brain structure. Genome-wide association studies suggest that anhedonia is heritable, with a polygenic architecture, but few studies have explored the association between genetic loadin...

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Bibliographic Details
Main Authors: Xingxing Zhu, Joey Ward, Breda Cullen, Donald M. Lyall, Rona J. Strawbridge, Laura M. Lyall, Daniel J. Smith
Format: Article
Language:English
Published: Nature Publishing Group 2021-07-01
Series:Translational Psychiatry
Online Access:https://doi.org/10.1038/s41398-021-01522-4