Silencing Huntington's chorea: Is RNA Interference a Potential Cure?

In 1872, George Huntington described Huntington's disease as characterized by motor, cognitive and psychiatric impairments. Huntington's disease is a dominant and autosomal mutation on chromosome 4 featuring the insertion of numerous CAG repeats. CAG codes for the amino acid, glutmanine th...

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Bibliographic Details
Main Authors: Gerlinde A. Metz, Ian Q. Whishaw, Afra Foroud, Nafisa M. Jadavji
Format: Article
Language:English
Published: Appalachian State University Honors College 2006-01-01
Series:Impulse: The Premier Undergraduate Neuroscience Journal
Subjects:
Online Access:http://impulse.appstate.edu/sites/impulse.appstate.edu/files/2006_11_14_jadavji2.pdf