Episodic evolution of coadapted sets of amino acid sites in mitochondrial proteins.

The rate of evolution differs between protein sites and changes with time. However, the link between these two phenomena remains poorly understood. Here, we design a phylogenetic approach for distinguishing pairs of amino acid sites that evolve concordantly, i.e., such that substitutions at one site...

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Bibliographic Details
Main Authors: Alexey D Neverov, Anfisa V Popova, Gennady G Fedonin, Evgeny A Cheremukhin, Galya V Klink, Georgii A Bazykin
Format: Article
Language:English
Published: Public Library of Science (PLoS) 2021-01-01
Series:PLoS Genetics
Online Access:https://doi.org/10.1371/journal.pgen.1008711