All-Optical Electrophysiology in hiPSC-Derived Neurons With Synthetic Voltage Sensors

All-Optical Electrophysiology in hiPSC-Derived Neurons With Synthetic Voltage Sensors

Voltage imaging and “all-optical electrophysiology” in human induced pluripotent stem cell (hiPSC)-derived neurons have opened unprecedented opportunities for high-throughput phenotyping of activity in neurons possessing unique genetic backgrounds of individual patients. While prior all-optical elec...

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Bibliographic Details
Main Authors: Francesca Puppo, Sanaz Sadegh, Cleber A. Trujillo, Martin Thunemann, Evan P. Campbell, Matthieu Vandenberghe, Xiwei Shan, Ibrahim A. Akkouh, Evan W. Miller, Brenda L. Bloodgood, Gabriel A. Silva, Anders M. Dale, Gaute T. Einevoll, Srdjan Djurovic, Ole A. Andreassen, Alysson R. Muotri, Anna Devor
Format: Article
Language:English
Published: Frontiers Media S.A. 2021-05-01
Series:Frontiers in Cellular Neuroscience
Subjects:
stem cells
voltage imaging
BeRST-1
phenotyping
optogenetics
Online Access:https://www.frontiersin.org/articles/10.3389/fncel.2021.671549/full

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https://www.frontiersin.org/articles/10.3389/fncel.2021.671549/full

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