Characterization of the Hypothalamic-Pituitary-Adrenal-Axis in Familial Longevity under Resting Conditions.

The hypothalamic-pituitary-adrenal (HPA)-axis is the most important neuro-endocrine stress response system of our body which is of critical importance for survival. Disturbances in HPA-axis activity have been associated with adverse metabolic and cognitive changes. Humans enriched for longevity have...

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Bibliographic Details
Main Authors: Steffy W Jansen, Ferdinand Roelfsema, Abimbola A Akintola, Nicole Y Oei, Christa M Cobbaert, Bart E Ballieux, Jeroen van der Grond, Rudi G Westendorp, Hanno Pijl, Diana van Heemst
Format: Article
Language:English
Published: Public Library of Science (PLoS) 2015-01-01
Series:PLoS ONE
Online Access:http://europepmc.org/articles/PMC4508039?pdf=render