Gilteritinib in the treatment of relapsed and refractory acute myeloid leukemia with a FLT3 mutation

Acute myeloid leukemia (AML) is a malignancy of uncontrolled proliferation of immature myeloid blasts characterized by clonal evolution and genetic heterogeneity. FMS-like tyrosine kinase 3 (FLT3) mutations occur in up to a third of AML cases and are associated with highly proliferative disease, sho...

Full description

Bibliographic Details
Main Authors: Serena Chew, Melissa C. Mackey, Elias Jabbour
Format: Article
Language:English
Published: SAGE Publishing 2020-06-01
Series:Therapeutic Advances in Hematology
Online Access:https://doi.org/10.1177/2040620720930614