Gilteritinib in the treatment of relapsed and refractory acute myeloid leukemia with a FLT3 mutation
Acute myeloid leukemia (AML) is a malignancy of uncontrolled proliferation of immature myeloid blasts characterized by clonal evolution and genetic heterogeneity. FMS-like tyrosine kinase 3 (FLT3) mutations occur in up to a third of AML cases and are associated with highly proliferative disease, sho...
Main Authors: | , , |
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Format: | Article |
Language: | English |
Published: |
SAGE Publishing
2020-06-01
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Series: | Therapeutic Advances in Hematology |
Online Access: | https://doi.org/10.1177/2040620720930614 |