The Treg/Th17 axis: A dynamic balance regulated by the gut microbiome

T-helper 17 (Th17) and T-regulatory (Treg) cells are frequently found at barrier surfaces, particularly within the intestinal mucosa, where they function to protect the host from pathogenic microorganisms and to restrain excessive effector T-cell responses, respectively. Despite their differing func...

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Bibliographic Details
Main Authors: Sara eOmenetti, Theresa T. Pizarro
Format: Article
Language:English
Published: Frontiers Media S.A. 2015-12-01
Series:Frontiers in Immunology
Subjects:
Online Access:http://journal.frontiersin.org/Journal/10.3389/fimmu.2015.00639/full