Transcryptomic Analysis of Human Brain Microvascular Endothelial Response to-Pericytes: Cell Orientation Defines Barrier Function

Transcryptomic Analysis of Human Brain Microvascular Endothelial Response to-Pericytes: Cell Orientation Defines Barrier Function

Pericytes facilitate blood–brain barrier (BBB) integrity; however, the mechanisms involved remain unclear. Hence, using co-cultures of human cerebral microvascular endothelial cells (ECs) and vascular pericytes (PCs) in different spatial arrangements, as well as PC conditioned media, we investigated...

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Bibliographic Details
Main Authors: Lisa Kurmann, Michal Okoniewski, Omolara O. Ogunshola, Brigitte Leeners, Bruno Imthurn, Raghvendra K. Dubey
Format: Article
Language:English
Published: MDPI AG 2021-04-01
Series:Cells
Subjects:
pericyte
hCMEC/D3
co-culture
blood–brain barrier
orientation
transcriptome
Online Access:https://www.mdpi.com/2073-4409/10/4/963

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https://www.mdpi.com/2073-4409/10/4/963

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