Low Field NMR Determination of pKa Values for Hydrophilic Drugs for Students in Medicinal Chemistry

Low Field NMR Determination of pKa Values for Hydrophilic Drugs for Students in Medicinal Chemistry

For an interdisciplinary approach on different topics of medicinal and analytical chemistry, we applied a known experimental pKa value determination method on the field of the bench top nuclear magnetic resonance (NMR) spectrometry of some known biologically active pyridine-based drugs, i.e., pyrido...

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Bibliographic Details
Main Authors: Aleksandra Zivkovic, Jan Josef Bandolik, Alexander Jan Skerhut, Christina Coesfeld, Miomir Raos, Nenad Zivkovic, Vlastimir Nikolic, Holger Stark
Format: Article
Language:English
Published: MDPI AG 2017-09-01
Series:Magnetochemistry
Subjects:
pKa value
low field NMR
molecular properties
pharmacokinetics
undergraduate pharmacy students
Online Access:https://www.mdpi.com/2312-7481/3/3/29

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https://www.mdpi.com/2312-7481/3/3/29

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