Group A Streptococcus Subcutaneous Infection-Induced Central Nervous System Inflammation Is Attenuated by Blocking Peripheral TNF

Group A Streptococcus Subcutaneous Infection-Induced Central Nervous System Inflammation Is Attenuated by Blocking Peripheral TNF

Group A streptococcus (GAS) infection causes a strong inflammatory response associated with cytokine storms, leading to multiorgan failure, which is characterized as streptococcal toxic shock syndrome. However, little is known about GAS subcutaneous infection-mediated brain inflammation. Therefore,...

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Bibliographic Details
Main Authors: Ya-Hui Liu, Pei-Hua Wu, Chih-Cheng Kang, Yau-Sheng Tsai, Chuan-Kai Chou, Chung-Tiang Liang, Jiunn-Jong Wu, Pei-Jane Tsai
Format: Article
Language:English
Published: Frontiers Media S.A. 2019-02-01
Series:Frontiers in Microbiology
Subjects:
Streptococcus pyogenes
TNF
central nervous system inflammation
NF-κB activation
reporter mice
Online Access:https://www.frontiersin.org/article/10.3389/fmicb.2019.00265/full

Internet

https://www.frontiersin.org/article/10.3389/fmicb.2019.00265/full

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