Urokinase-type plasminogen activator supports liver repair independent of its cellular receptor

<p>Abstract</p> <p>Background</p> <p>The urokinase-type (uPA) and tissue-type (tPA) plasminogen activators regulate liver matrix remodelling through the conversion of plasminogen (Plg) to the active protease plasmin. Based on the efficient activation of plasminogen when...

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Bibliographic Details
Main Authors: Bezerra Jorge A, Degen Jay L, Sabla Gregg E, Shanmukhappa Kumar
Format: Article
Language:English
Published: BMC 2006-11-01
Series:BMC Gastroenterology
Online Access:http://www.biomedcentral.com/1471-230X/6/40