An Efficient Estimator of the Mutation Parameter and Analysis of Polymorphism from the 1000 Genomes Project
The mutation parameter θ is fundamental and ubiquitous in the analysis of population samples of DNA sequences. This paper presents a new highly efficient estimator of θ by utilizing the phylogenetic information among distinct alleles in a sample of DNA sequences. The new estimator, called Allelic BL...
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| Format: | Article |
| Language: | English |
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MDPI AG
2014-07-01
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| Series: | Genes |
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| Online Access: | http://www.mdpi.com/2073-4425/5/3/561 |