Sirt1 ameliorates chronic mild unpredictable stress-induced depression-like behaviors in mice by promoting hippocampal microglia M2 polarization
Objective To explore the effect of silent mating-type information regulation 2 homolog 1 (Sirt1) on depression-like behaviors in mice and the underlying molecular mechanism. Methods Forty 8-week-old male C57BL/6 mice were subjected to chronic mild unpredictable stress (CUMS) to establish models of d...
Main Authors: | WANG Yue, WAN Tengfei, DUAN Chunme, WANG Li, CHEN Xiaoyan |
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Format: | Article |
Language: | zho |
Published: |
Editorial Office of Journal of Third Military Medical University
2019-07-01
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Series: | Di-san junyi daxue xuebao |
Subjects: | |
Online Access: | http://aammt.tmmu.edu.cn/Upload/rhtml/201901077.htm |
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