Hepatic Steatosis Contributes to the Development of Muscle Atrophy via Inter-Organ Crosstalk

Hepatic Steatosis Contributes to the Development of Muscle Atrophy via Inter-Organ Crosstalk

Individuals with hepatic steatosis often display several metabolic abnormalities including insulin resistance and muscle atrophy. Previously, we found that hepatic steatosis results in an altered hepatokine secretion profile, thereby inducing skeletal muscle insulin resistance via inter-organ crosst...

Full description

Bibliographic Details
Main Authors: Kenneth Pasmans, Michiel E. Adriaens, Peter Olinga, Ramon Langen, Sander S. Rensen, Frank G. Schaap, Steven W. M. Olde Damink, Florian Caiment, Luc J. C. van Loon, Ellen E. Blaak, Ruth C. R. Meex
Format: Article
Language:English
Published: Frontiers Media S.A. 2021-10-01
Series:Frontiers in Endocrinology
Subjects:
hepatic steatosis
NAFLD
inter-organ crosstalk
muscle atrophy
sarcopenia
insulin resistance, metabolism
Online Access:https://www.frontiersin.org/articles/10.3389/fendo.2021.733625/full

Internet

https://www.frontiersin.org/articles/10.3389/fendo.2021.733625/full

Similar Items