The Importance of Hypoxia-Inducible Factors (HIF-1 and HIF-2) for the Pathophysiology of Inflammatory Bowel Disease

The Importance of Hypoxia-Inducible Factors (HIF-1 and HIF-2) for the Pathophysiology of Inflammatory Bowel Disease

(1) Background: Hypoxia is a common feature of inflammation when hypoxia inducible factors (HIFs) adapt cells to conditions of low oxygen tension and inflammation. We studied the role of HIF-1 and HIF-2 in cells of the myeloid lineage in a mouse model of acute colitis. (2) Methods: Mice with and wit...

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Bibliographic Details
Main Authors: Evelyn L. Kerber, Claudia Padberg, Nora Koll, Vera Schuetzhold, Joachim Fandrey, Sandra Winning
Format: Article
Language:English
Published: MDPI AG 2020-11-01
Series:International Journal of Molecular Sciences
Subjects:
IBD
inflammation
HIF-1
HIF-2
Online Access:https://www.mdpi.com/1422-0067/21/22/8551

Internet

https://www.mdpi.com/1422-0067/21/22/8551

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