Antioxidant Small Molecule Compound Chrysin Promotes the Self-Renewal of Hematopoietic Stem Cells

Antioxidant Small Molecule Compound Chrysin Promotes the Self-Renewal of Hematopoietic Stem Cells

There is an increasing demand for the expansion of functional human hematopoietic stem cells (hHSCs) for various clinical applications. Based on our primary screening of antioxidant small molecule compounds library, a small molecule compound C2968 (chrysin) was identificated to expand cord blood CD3...

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Bibliographic Details
Main Authors: Yinghui Li, Mei He, Wenshan Zhang, Ming Yang, Yahui Ding, Shiqi Xu, Jiali Gu, Yafang Li, Jingjing Yin, Yingdai Gao
Format: Article
Language:English
Published: Frontiers Media S.A. 2020-04-01
Series:Frontiers in Pharmacology
Subjects:
antioxidant
small molecule compound
chrysin
ex vivo expansion
hematopoietic stem cells
self-renewal
Online Access:https://www.frontiersin.org/article/10.3389/fphar.2020.00399/full

Internet

https://www.frontiersin.org/article/10.3389/fphar.2020.00399/full

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