Prognostic Significance of CHIP and RIPK3 in Non-Small Cell Lung Cancer

Prognostic Significance of CHIP and RIPK3 in Non-Small Cell Lung Cancer

RIPK3 is a key regulator of necroptosis, which plays a double-edged sword role in tumor progression. CHIP is an E3 ubiquitin ligase that regulates necroptosis by degrading RIPK3. Here, we investigated the prognostic value of RIPK3 and CHIP expression in 404 patients with non-small cell lung cancer (...

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Bibliographic Details
Main Authors: Jisup Kim, Joon-Yong Chung, Young Soo Park, Se Jin Jang, Hyeong Ryul Kim, Chang-Min Choi, Joon Seon Song
Format: Article
Language:English
Published: MDPI AG 2020-06-01
Series:Cancers
Subjects:
necroptosis
carboxyl terminus of Hsp70-interacting protein (CHIP)
receptor interacting serine/threonine kinase 3 (RIPK3)
prognosis
non-small cell lung cancer
Online Access:https://www.mdpi.com/2072-6694/12/6/1496

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https://www.mdpi.com/2072-6694/12/6/1496

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