Different distribution of neuromedin S (NMS) and its mRNA in the rat brain: NMS peptide is present not only in the hypothalamus as the mRNA, but also in the brainstem

Different distribution of neuromedin S (NMS) and its mRNA in the rat brain: NMS peptide is present not only in the hypothalamus as the mRNA, but also in the brainstem

Neuromedin S (NMS) is a neuropeptide identified as another endogenous ligand for two orphan G protein-coupled receptors, FM-3/GPR66 and FM-4/TGR-1, which have also been identified as types 1 and 2 receptors for neuromedin U structurally related to NMS. Although expression of NMS mRNA is found mainly...

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Bibliographic Details
Main Authors: Miwa eMori, Kenji eMori, Takanori eIda, Takahiro eSato, Masayasu eKojima, Mikiya eMiyazato, Kenji eKangawa
Format: Article
Language:English
Published: Frontiers Media S.A. 2012-12-01
Series:Frontiers in Endocrinology
Subjects:
Brain
Radioimmunoassay
brainstem
Neuropeptide
neuromedin S
peptide distribution
Online Access:http://journal.frontiersin.org/Journal/10.3389/fendo.2012.00152/full

Internet

http://journal.frontiersin.org/Journal/10.3389/fendo.2012.00152/full

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