Human Germline: A New Research Frontier

We recently elucidated the mechanism of human primordial germ cell (hPGC) specification and resetting of the epigenome for totipotency. The regulators of hPGC specification also initiate resetting of the epigenome, leading to a comprehensive erasure of DNA methylation, erasure of imprints and X reac...

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Bibliographic Details
Main Author: M. Azim Surani
Format: Article
Language:English
Published: Elsevier 2015-06-01
Series:Stem Cell Reports
Online Access:http://www.sciencedirect.com/science/article/pii/S2213671115001265