An mRNA Vaccine Protects Mice against Multiple Tick-Transmitted Flavivirus Infections

Summary: Powassan virus (POWV) is an emerging tick-transmitted flavivirus that circulates in North America and Russia. Up to 5% of deer ticks now test positive for POWV in certain regions of the northern United States. Although POWV infections cause life-threatening encephalitis, there is no vaccine...

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Bibliographic Details
Main Authors: Laura A. VanBlargan, Sunny Himansu, Bryant M. Foreman, Gregory D. Ebel, Theodore C. Pierson, Michael S. Diamond
Format: Article
Language:English
Published: Elsevier 2018-12-01
Series:Cell Reports
Online Access:http://www.sciencedirect.com/science/article/pii/S2211124718318734