A Non-Canonical Calmodulin Target Motif Comprising a Polybasic Region and Lipidated Terminal Residue Regulates Localization

A Non-Canonical Calmodulin Target Motif Comprising a Polybasic Region and Lipidated Terminal Residue Regulates Localization

Calmodulin (CaM) is a Ca<sup>2+</sup>-sensor that regulates a wide variety of target proteins, many of which interact through short basic helical motifs bearing two hydrophobic ‘anchor’ residues. CaM comprises two globular lobes, each containing a pair of EF-hand Ca<sup>2+</sup&...

Full description

Bibliographic Details
Main Authors: Benjamin M.M. Grant, Masahiro Enomoto, Mitsuhiko Ikura, Christopher B. Marshall
Format: Article
Language:English
Published: MDPI AG 2020-04-01
Series:International Journal of Molecular Sciences
Subjects:
Calmodulin
KRAS4b
prenylation
myristoylation
polybasic region
Ca2+ signaling
Online Access:https://www.mdpi.com/1422-0067/21/8/2751

Internet

https://www.mdpi.com/1422-0067/21/8/2751

Similar Items