The co-culture of ASCs and EPCs promotes vascularized bone regeneration in critical-sized bone defects of cranial bone in rats

Abstract Background The repair of critical-sized bone defect represents a challenging problem in bone tissue engineering. To address the most important problem in bone defect repair, namely insufficient blood supply, this study aimed to find a method that can promote the formation of vascularized bo...

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Bibliographic Details
Main Authors: Yuanjia He, Shuang Lin, Qiang Ao, Xiaoning He
Format: Article
Language:English
Published: BMC 2020-08-01
Series:Stem Cell Research & Therapy
Subjects:
Online Access:http://link.springer.com/article/10.1186/s13287-020-01858-6