AZD5153 Inhibits Prostate Cancer Cell Growth in Vitro and in Vivo

AZD5153 Inhibits Prostate Cancer Cell Growth in Vitro and in Vivo

Backgrounds/Aims: Bromodomain-containing protein 4 (BRD4) overexpression participates in prostate cancer progression by enhancing the transcriptional activity and expression of several key oncogenes. AZD5153 is a novel BRD4 inhibitor. Methods: Prostate cancer cells were treated with AZD5153. Cell su...

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Bibliographic Details
Main Authors: Gang Shen, Jianchun Chen, Yongqiang Zhou, Zhenfan Wang, Zheng Ma, Chen Xu, Minjun Jiang
Format: Article
Language:English
Published: Cell Physiol Biochem Press GmbH & Co KG 2018-10-01
Series:Cellular Physiology and Biochemistry
Subjects:
Prostate cancer
BRD4
AZD5153
AKT
Chemosensitization
Online Access:https://www.karger.com/Article/FullText/494244

Internet

https://www.karger.com/Article/FullText/494244

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